MORPHOLOGICAL ORGAN REMODELLING CAUSED BY OPIOID ANALGESICS

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Opioid Analgesics

Intensive research on the neurobiology of pain over the past two decades has revealed many receptors, ion channels and enzymes with potential as novel targets for development of a new generation of analgesic agents. However, despite large investment in preclinical and clinical development of small molecules and biologics as potential novel pain therapeutics, very few have reached the clinic. He...

متن کامل

Non-opioid analgesics

C describe the concept of multimodal analgesia and give examples Abstract Opium is the natural substance to which modern narcotics owe their existence. First discovered in the 1500s, opium was the most potent analgesic compound in use, held in high regard, hence its Latin name laudanum (to praise). Subsequent studies into the effects of opium led to the discovery of the opioid receptors, and th...

متن کامل

Opioid analgesics in palliative care

The discovery of the opioid receptors began in the 1970s and three (μ, δ and κ) are now recognised. Most current opioid analgesics interact preferentially with μ receptors, although some have actions at δ and κ receptors. The revelation that opioid receptors are present on peripheral sensory neurones and immune system cells, has led to the realisation that the opioid system is involved in a hos...

متن کامل

The Future Of Opioid Analgesics

PROLOGUE The opioid analgesics represent an important class of agents for the treatment of severe clinical pain, but many effects often limit their usefulness. This manuscript will discuss recent findings in opioid pharmacology, and how medicinal chemists may be able to utilize these findings of novel opioid analgesics with reduced undesired effects. As such, the manuscript serves as an example...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії

سال: 2020

ISSN: 2077-1126,2077-1096

DOI: 10.31718/2077-1096.20.3.258